{"id":4424,"date":"2025-04-15T16:39:00","date_gmt":"2025-04-15T21:39:00","guid":{"rendered":"https:\/\/mickeylieberman.com\/alzheimers\/?p=4424"},"modified":"2025-03-06T14:27:00","modified_gmt":"2025-03-06T19:27:00","slug":"what-are-the-neurological-causes-of-alzheimers-disease","status":"publish","type":"post","link":"https:\/\/mickeylieberman.com\/alzheimers\/what-are-the-neurological-causes-of-alzheimers-disease\/","title":{"rendered":"What are the Neurological Causes of Alzheimer’s Disease?"},"content":{"rendered":"

Neurological Causes of Alzheimer’s Disease<\/span><\/p>\n

The actual causes of Alzheimer’s disease remain elusive.<\/span><\/p>\n

Researchers have made some progress in understanding what causes this debilitating condition.<\/span><\/p>\n

The disease is named after Alois Alzheimer.<\/span><\/p>\n

He was the first to identify the peculiar plaques and tangles in the brain, which are characteristic of the illness.<\/span><\/p>\n

Not until the final decades of the twentieth century, Alzheimer’s could only be accurately diagnosed by a post-mortem examination and the careful analysis of the brain tissues.<\/span><\/p>\n

Due to the ongoing research, scientists are beginning to uncover precisely what is happening and why those characteristic tangles and plaques crop up in the brain.<\/span><\/p>\n

Many of the symptoms of Alzheimer’s disease are caused by neurofibrillary tangles in the brain. Microscopic filaments clog the neurons.<\/span><\/p>\n

These filaments are made up of an abnormal kind of protein.<\/span><\/p>\n

In a normal brain, there is constant transmission of messages from one neuron to another.<\/span><\/p>\n

But in an Alzheimer’s brain, instead of bonding into message pathways,\u00a0 the neuron messages go nowhere and there is no communication.<\/span><\/p>\n

Since the neurons are clogged, signals from the environment are no longer transmitted the way they should be.<\/span><\/p>\n

That is why severe cognitive impairment is one of the symptoms of Alzheimer’s disease.<\/span><\/p>\n

There is a protein called beta-amyloid that causes plaque to develop between the neurons.<\/span><\/p>\n

This results in the other main damage to the brain in Alzheimer’s disease.<\/span><\/p>\n

The plaque deposits are sticky patches in the brain which contain beta-amyloid protein.<\/span><\/p>\n

The plaque blocks communication pathways between neurons, which results in memory problems and learning abilities associated with Alzheimer’s disease.<\/span><\/p>\n

The degree of cognitive impairment depends on the amount of plaque present.<\/span><\/p>\n

Acetylcholine, which helps to transmit nerve messages, does not function properly because of the buildup of plaque.<\/span><\/p>\n

The treatment for Alzheimer’s disease involves using acetylcholinesterase inhibitors, which work by blocking enzymes that consume acetylcholine.<\/span><\/p>\n

This medication is effective during the early stages of the disease before too much plaque has already built up.<\/span><\/p>\n

Some research seems to indicate that the plaque causes tangles.<\/span><\/p>\n

Others believe that both plaques and tangles are the results of other processes. One possible culprit is swollen axons.<\/span><\/p>\n

Axons are critical for transmitting messages between neurons.<\/span><\/p>\n

When axons swell, they may block message transmission and perhaps lead to the plaques and tangles which bring on Alzheimer’s disease.<\/span><\/p>\n

Scientists are working hard to uncover and identify the causes of Alzheimer’s disease, which may sooner or later lead to a comprehensive cure for this dreaded condition.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Neurological Causes of Alzheimer’s Disease The actual causes of Alzheimer’s disease remain elusive. Researchers have made some progress in understanding what causes this debilitating condition….<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"slim_seo":{"title":"What are the Neurological Causes of Alzheimer's Disease? - Alzheimer's and Dementia","description":"Neurological Causes of Alzheimer's Disease The actual causes of Alzheimer's disease remain elusive. Researchers have made some progress in understanding what ca"},"_slim_seo_primary_term_category":0,"_slim_seo_primary_term_post_tag":0,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-4424","post","type-post","status-publish","format-standard","hentry","category-alzheimers-and-dmenetia","wpcat-1-id"],"_links":{"self":[{"href":"https:\/\/mickeylieberman.com\/alzheimers\/wp-json\/wp\/v2\/posts\/4424","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mickeylieberman.com\/alzheimers\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mickeylieberman.com\/alzheimers\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mickeylieberman.com\/alzheimers\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/mickeylieberman.com\/alzheimers\/wp-json\/wp\/v2\/comments?post=4424"}],"version-history":[{"count":0,"href":"https:\/\/mickeylieberman.com\/alzheimers\/wp-json\/wp\/v2\/posts\/4424\/revisions"}],"wp:attachment":[{"href":"https:\/\/mickeylieberman.com\/alzheimers\/wp-json\/wp\/v2\/media?parent=4424"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mickeylieberman.com\/alzheimers\/wp-json\/wp\/v2\/categories?post=4424"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mickeylieberman.com\/alzheimers\/wp-json\/wp\/v2\/tags?post=4424"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}